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American Society of Microbiology ABMM Exam Syllabus Topics:

American Society of Microbiology ABMM Sample Questions:

1. A patient with a history of travel to South America presents with fever, lymphadenopathy, and hepatosplenomegaly. Peripheral blood smear reveals the presence of trypomastigotes. The MOST likely diagnosis is:

A) African trypanosomiasis (sleeping sickness)
B) Malaria
C) Chagas disease (American trypanosomiasis)
D) Leishmaniasis

2. A Gram stain of anaerobic growth from a peritoneal fluid abscess reveals pleomorphic, pale-staining Gram- negative rods. The isolate grows on Bacteroides Bile Esculin (BBE) agar, hydrolyzing esculin (producing black colonies), and is resistant to kanamycin (1000 µg), vancomycin (5 µg), and colistin (10 µg) disks. Which organism group is most likely?

A) Fusobacterium nucleatum
B) Prevotella melaninogenica group
C) Bacteroides fragilis group
D) Clostridium perfringens

3. A microbiology laboratory receives a bronchoalveolar lavage sample from a patient with suspected ventilator- associated pneumonia. Quantitative culture yields >10^5 CFU/mL of a Gram-negative rod. Identification reveals Stenotrophomonas maltophilia. The MOST significant resistance mechanism commonly associated with this organism is:

A) Ribosomal methylation leading to macrolide resistance.
B) Production of extended-spectrum beta-lactamases (ESBLs).
C) Intrinsic resistance mediated by efflux pumps and specific enzymes.
D) Target site modification in DNA gyrase.

4. A patient presents with a pruritic rash consisting of raised, serpiginous tracks on their skin. The patient recently returned from a Caribbean vacation and reported walking barefoot on the beach. The MOST likely causative organism is:

A) Larvae of Ancylostoma braziliense
B) Pediculus humanus
C) Larvae of Strongyloides stercoralis
D) Sarcoptes scabiei

5. A patient presents with symptoms suggestive of primary syphilis. Which diagnostic test typically becomes positive earliest in the course of infection?

A) Treponema pallidum particle agglutination (TP-PA)
B) Venereal Disease Research Laboratory (VDRL) test on CSF
C) Darkfield microscopy of lesion exudate
D) Rapid Plasma Reagin (RPR)

Solutions: